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Sodium carboxy methyl cellulose (E 466) is white when pure; industrial grade material may be grayish-white or cream granules or powder.
Sodium carboxy methyl cellulose (E 466) is the substituted product of cellulosic carboxymethyl group.
Sodium carboxy methyl cellulose (E 466) for oenological use is prepared exclusively from wood by treatment with alkali and monochloroacetic acid or its sodium salt.
CAS Number: 9004-32-4
Molecular Formula: C6H7O2(OH)2CH2COONa
EINECS Number: 618-378-6
Synonyms: Sodium carboxy methyl cellulose (E 466), 9004-32-4, sodium;2,3,4,5,6-pentahydroxyhexanal;acetate
Carboxymethylcellulose sodium (USP),Carboxymethylcellulose cellulose carboxymethyl ether, CMC powder,Celluvisc (TN),Carmellose sodium (JP17),CHEMBL242021,C.M.C. (TN), CHEBI:31357,E466,Sodium carboxy methyl cellulose (E 466) (MW 250000),D01544
Sodium carboxy methyl cellulose (E 466) a colorless, odorless, water-soluble polymer.
Sodium carboxy methyl cellulose (E 466), NaCMC or CMC, was first developed in 1947.
Commonly known as carboxymethyl cellulose, it is composed of the sodium salt of an alkaline modified cellulose.
Sodium carboxy methyl cellulose (E 466) is water-soluble but will react with heavy metal salts to form films that are clear, tough and insoluble in water.
According to their molecular weight or degree of substitution, Sodium carboxy methyl cellulose (E 466) can be completely dissolved or insoluble polymer, the latter can be used as the weak acid cation of exchanger to separate neutral or basic proteins.
Sodium carboxy methyl cellulose (E 466) can form highly viscous colloidal solution with adhesive, thickening, flowing, emulsifying, shaping, water, protective colloid, film forming, acid, salt, suspensions and other characteristics, and it is physiologically harmless, so it is widely used in the food, pharmaceutical, cosmetic, oil, paper, textiles, construction and other areas of production.
Sodium carboxy methyl cellulose (E 466) is a white or slightly yellowish powder.
Sodium carboxy methyl cellulose (E 466) or cellulose gum is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
Sodium carboxy methyl cellulose (E 466) is often used as its sodium salt, Sodium carboxy methyl cellulose (E 466).
Sodium carboxy methyl cellulose (E 466) used to be marketed under the name Tylose, a registered trademark of SE Tylose.
A semisynthetic, water-soluble polymer in which CH 2 COOH groups are substituted on the glucose units of the cellulose chain through an ether link- age.
Since the reaction occurs in an alkaline medium, the prod- uct is the sodium salt of the carboxylic acid R-O- CH 2 COONa.
Sodium carboxy methyl cellulose (E 466) is tackifier, at room temperature, it is non-toxic tasteless white flocculent powder, it is stable and soluble in water, aqueous solution is neutral or alkaline transparent viscous liquid, it is soluble in other water-soluble gums and resins, it is insoluble in organic solvents such as ethanol.
Sodium carboxy methyl cellulose (E 466) is also an especially effective binder that can be used in small amounts in compositions, where the binder can intcrfere with the intended effect (e.g., in strobe compositions).
Sodium carboxy methyl cellulose (E 466) is also a natural polymeric derivative that can be used in detergents, food and textile industries.
Sodium carboxy methyl cellulose (E 466) is a water-soluble polymer.
As a solution in water, Sodium carboxy methyl cellulose (E 466) has thixotropic properties.
Sodium carboxy methyl cellulose (E 466) is a white or slightly yellowish, almost odourless and tasteless hydroscopic powder, consisting of very fine particles, fine granules or fine fibres.
Sodium carboxy methyl cellulose (E 466) is biodegradable, but not readily biodegradable, and it is not expected to bioaccumulate.
Sodium carboxy methyl cellulose (E 466) is components consist of polysaccharide composed of fibrous tissues of plants.
Sodium carboxy methyl cellulose (E 466) is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.
Sodium carboxy methyl cellulose (E 466) is a water soluble polymer which can be used as a polyelectrolyte cellulose derivative.
Sodium carboxy methyl cellulose (E 466) belongs to the class of anionic linear structured cellulose.
Sodium carboxy methyl cellulose (E 466) is thixotropic, becoming less viscous when agitated.
Sodium carboxy methyl cellulose (E 466) is widely used in oral and topical pharmaceutical formulations, primarily for its viscosity-increasing properties.
Viscous aqueous solutions are used to suspend powders intended for either topical application or oral and parenteral administration.
Sodium carboxy methyl cellulose (E 466) may also be used as a tablet binder and disintegrant, and to stabilize emulsions.
This muco-adhesive property is used in products designed to prevent post-surgical tissue adhesions; and to localize and modify the release kinetics of active ingredients applied to mucous membranes; and for bone repair.
Encapsulation with carboxymethylcellulose sodium can affect drug protection and delivery.
There have also been reports of its use as a cyto-protective agent.
Higher concentrations, usually 3–6%, of the medium-viscosity grade are used to produce gels that can be used as the base for applications and pastes; glycols are often included in such gels to prevent them drying out.
Sodium carboxy methyl cellulose (E 466) is also used in self-adhesive ostomy, wound care, and dermatological patches as a muco-adhesive and to absorb wound exudate or transepidermal water and sweat.
In most cases, Sodium carboxy methyl cellulose (E 466) functions as a polyelectrolyte.
Sodium carboxy methyl cellulose (E 466) is used commercially in detergents, food product and as size for textiles and paper.
In conservation, Sodium carboxy methyl cellulose (E 466) has been used as an adhesive for textiles and paper.
Sodium carboxy methyl cellulose (E 466) is also used in cosmetics, toiletries, surgical prosthetics, and incontinence, personal hygiene, and food products.
Sodium carboxy methyl cellulose (E 466) is one of the most significant byproducts of cellulose ethers which are created by natural cellulose modification as a type of cellulose derivate with an ether structure.
Termed Sodium carboxy methyl cellulose (E 466), this polymer has a poor water solubility of the acid form of CMC and is typically preserved as sodium carboxymethylcellulose.
Sodium carboxy methyl cellulose (E 466) is utilized in numerous industries and is referred to as monosodium glutamate in the workplace.
Sodium carboxy methyl cellulose (E 466) is an offshoot of CMC.
Since the Sodium carboxy methyl cellulose (E 466) compound is typically poorly soluble in water, sodium CMC can be used to preserve it.
Sodium carboxy methyl cellulose (E 466) is suitable for use in food systems.
Sodium carboxy methyl cellulose (E 466) is physiologically inert.
Sodium carboxy methyl cellulose (E 466) is an anionic polyelectrolyte.
Sodium carboxy methyl cellulose (E 466) has dispersibility and is soluble in cold water.
Emulsifying dispersion and solid dispersion are two of sodium Sodium carboxy methyl cellulose (E 466)'s peculiar chemical properties.
Sodium carboxy methyl cellulose (E 466) can be categorized as a derivative of a natural polymer.
Sodium carboxy methyl cellulose (E 466) is also available in several different viscosity grades.
Sodium carboxy methyl cellulose (E 466) is highly soluble in water at all temperatures, forming clear solutions.
Sodium carboxy methyl cellulose (E 466)s solubility depends on its degree of substitution.
Sodium carboxy methyl cellulose (E 466), one of major cellulosic ethers, is widely used as a binding, thickening and stabilising agent (Lee et al. 2018).
Pharmaceutical grades of Sodium carboxy methyl cellulose (E 466) are available commercially at degree of substitution (DS) values of 0.7, 0.9, and 1.2, with a corresponding sodium content of 6.5%–12% wt.
Sodium carboxy methyl cellulose (E 466) is a crucial by-product of cellulose ethers and is typically created by altering natural cellulose.
Aging studies indicate that most Sodium carboxy methyl cellulose (E 466) polymers have very good stability with negligible discoloration or weight loss.
Sodium carboxy methyl cellulose (E 466) is an anionic water-soluble polymer based on renewable cellulosic raw material.
Sodium carboxy methyl cellulose (E 466) functions as a rheology modifier, binder, dispersant, and an excellent film former.
These attributes make Sodium carboxy methyl cellulose (E 466) a preferred choice as a bio-based hydrocolloid in multiple applications.
Sodium carboxy methyl cellulose (E 466) acts as a thickener, binder, stabilizer, suspending agent and flow controlling agent.
Sodium carboxy methyl cellulose (E 466) forms fine films that are resistant to oils, greases, and organic solvents.
Sodium carboxy methyl cellulose (E 466) dissolves rapidly in cold water. 4) Acts as a protective colloid reducing water losses.
Sodium carboxy methyl cellulose (E 466) is the sodium salt of carboxymethyl cellulose, an anionic derivative.
Sodium carboxy methyl cellulose (E 466) is a family of chemically modified cellulose derivatives containing the carboxymethyl ether group (-O-CH2-COO-) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
When Carboxymethylcellulose is recovered and presented as the Sodium salt, the resulting polymer is what is known as Sodium carboxy methyl cellulose (E 466), and has the general chemical formula, [C6H7O2(OH)x(OCH2COONa)y]n.
Sodium carboxy methyl cellulose (E 466) was discovered shortly after Word War 1 and has been produced commercially since the early 1930s.
Sodium carboxy methyl cellulose (E 466), often abbreviated as Na-CMC or simply CMC, is a versatile and widely used chemical compound.
Sodium carboxy methyl cellulose (E 466) is derived from cellulose, a natural polymer found in the cell walls of plants.
Sodium carboxy methyl cellulose (E 466) is a water-soluble polymer and is used for a variety of purposes in various industries, including food, pharmaceuticals, cosmetics, and more.
Sodium carboxy methyl cellulose (E 466) is produced by treating cellulose with an aqueous sodium hydroxide solution followed by monochloroacetic acid or its sodium salt.
Once these by-products are removed, high purity Sodium carboxymethylcellulose is obtained.
As a general rule, the obtained material has a slight excess of sodium hydroxide and has to be neutralised.
The neutralisation endpoint can affect the properties of the material.
In a parallel reaction two by-products, sodium chloride and sodium glycolate, are produced.
Sodium carboxy methyl cellulose (E 466) inhibits tartaric precipitation through a "protective colloid" effect.
Sodium carboxy methyl cellulose (E 466) is a low concern for toxicity to aquatic organisms.
Sodium carboxy methyl cellulose (E 466) is used for its thickening and swelling properties in a wide range of complex formulated products for pharmaceutical, food, home, and personal care applications, as well as in paper, water treatment, and mineral processing industries.
Sodium carboxy methyl cellulose (E 466) is a hygroscopic material that has the ability to absorb more than 50% of water at high humidity.
Sodium carboxy methyl cellulose (E 466) is useful in helping to hold the components of pyrotechnic compositions in aqucous suspension (e.g., in the making of black match).
Sodium carboxy methyl cellulose (E 466) is manufactured from cellulose by various proccsses that replacc some of the hy drogen atoms in the hydroxyl[OH] groups of the cellulose molecule with acidic carboxymethyl [-CH2CO.OH] groups，which are neutralized to form the corresponding sodium salt.
Melting point: 274 °C (dec.)
Density: 1,6 g/cm3
FEMA: 2239 | CARBOXYMETHYLCELLULOSE
storage temp.: room temp
solubility: H2O: 20 mg/mL, soluble
form: low viscosity
pka: 4.30(at 25℃)
color: White to light yellow
Odor: Odorless
PH Range: 6.5 - 8.5
PH: pH (10g/l, 25℃) 6.0～8.0
Sodium carboxy methyl cellulose (E 466) with a DS below 0.6 tends to be only partially soluble.
Sodium carboxy methyl cellulose (E 466) is used warm water or cold water when preparing the solution, and stir till it completely melts.
The amout of added water depends on variety and the use of multiple requirements.
Sodium carboxy methyl cellulose (E 466) is desirable because the catalysis product (glucose) is easily measured using a reducing sugar assay, such as 3,5-dinitrosalicylic acid.
Using Sodium carboxy methyl cellulose (E 466) in enzyme assays is especially important in screening for cellulase enzymes that are needed for more efficient cellulosic ethanol conversion.
Sodium carboxy methyl cellulose (E 466) was misused in early work with cellulase enzymes, as many had associated whole cellulase activity with CMC hydrolysis.
High viscosity Sodium carboxy methyl cellulose (E 466) is a white or slightly yellow fibrous powder, hygroscopic, odorless, tasteless, non-toxic, easy to ferment, insoluble in acids, alcohols and organic solvents, easily dispersed to form colloidal solution in water.
Alkali cellulose is prepared by steeping cellulose obtained from wood pulp or cotton fibers in sodium hydroxide solution.
Sodium carboxy methyl cellulose (E 466) is used warm water or cold water when preparing the solution, and stir till it completely melts.
The amout of added water depends on variety and the use of multiple requirements.
High viscosity Sodium carboxy methyl cellulose (E 466) is a white or slightly yellow fibrous powder, hygroscopic, odorless, tasteless, non-toxic, easy to ferment, insoluble in acids, alcohols and organic solvents, easily dispersed to form colloidal solution in water.
The alkaline cellulose is then reacted with sodium monochloroacetate to produce Sodium carboxy methyl cellulose (E 466).
Sodium carboxy methyl cellulose (E 466) is reacted by the acid and fibrous cotton, it is mainly used for water-based drilling fluids tackifier, it has certain role of fluid loss, it has strong salt and temperature resistance especially.
Sodium carboxy methyl cellulose (E 466) is incompatible with strongly acidic solutions and with the soluble salts of iron and some other metals, such as aluminum, mercury, and zinc.
Sodium carboxy methyl cellulose (E 466) is also incompatible with xanthan gum.
Precipitation may occur at pH < 2, and also when it is mixed with ethanol (95%).
Sodium carboxy methyl cellulose (E 466), is a cellulose derivative with 100-2000 degree of polymerization of glucose, and its relative molecular weight is 242.16.
White fibrous or granular powder.
Sodium carboxy methyl cellulose (E 466) is odourless, tasteless, tasteless, hygroscopic and insoluble in organic solvents.
Sodium carboxy methyl cellulose (E 466) forms complex coacervates with gelatin and pectin.
Sodium carboxy methyl cellulose (E 466) is one of the most important products of cellulose ethers, which are formed by natural cellulose modification as a kind of cellulose derivate with an ether structure.
Due to the fact that the acid form of Sodium carboxy methyl cellulose (E 466) has poor water solubility, it is usually preserved as sodium carboxymethylcellulose, which is widely used in many industries and regarded as monosodium glutamate in industry.
Sodium carboxy methyl cellulose (E 466) is used in cigarette adhesive, fabric sizing, footwear paste meal, home slimy.
Fabrics made of cellulose—e.g. cotton or viscose rayon—may also be converted into Sodium carboxy methyl cellulose (E 466).
Following the initial reaction, the resultant mixture produces approximately 60% Sodium carboxy methyl cellulose (E 466) and 40% salts (sodium chloride and sodium glycolate); this product is the so-called technical CMC, which is used in detergents.
An additional purification process is used to remove salts to produce pure Sodium carboxy methyl cellulose (E 466), which is used for alimentary and pharmaceutical applications.
An intermediate "semi-purified" grade is also produced, typically used in paper applications such as the restoration of archival documents.
Sodium carboxy methyl cellulose (E 466) is used as a thickener in the food industry, as a drug carrier in the pharmaceutical industry, as a binder and anti-retrogradation agent in the daily chemical industry.
Sodium carboxy methyl cellulose (E 466) is a water-soluble polymer derived from cellulose through a chemical modification process.
Sodium carboxy methyl cellulose (E 466) is a kind of cellulose widely used and used in the world today.
Sodium carboxy methyl cellulose (E 466) is used in interior painting architectural, building lines melamine, thickening mortar, concrete enhancement.
Sodium carboxy methyl cellulose (E 466) is synthesized by the alkali-catalyzed reaction of cellulose with chloroacetic acid.
Sodium chloride and sodium glycolate are obtained as by-products of this etherification.
Carboxymethyl groups (-CH2-COOH) are introduced into the cellulose structure.
These carboxymethyl groups make the cellulose molecule more water-soluble and provide it with its unique properties.
The viscosity of Sodium carboxy methyl cellulose (E 466) solutions can be controlled by adjusting the concentration of the polymer.
This property makes it suitable for a wide range of applications, from thin solutions in beverages to thick gels in some pharmaceutical formulations.
Sodium carboxy methyl cellulose (E 466) is stable over a wide pH range, making it suitable for use in both acidic and alkaline environments.
Sodium carboxy methyl cellulose (E 466) disperses easily in cold water, forming a smooth, uniform solution, which is advantageous in manufacturing processes.
Sodium carboxy methyl cellulose (E 466) can be used to form films or coatings.
This is particularly important in the food industry where it can be used in a variety of products with different pH levels.
Sodium carboxy methyl cellulose (E 466) is generally considered safe for consumption and topical use.
Sodium carboxy methyl cellulose (E 466) can be used to create edible films for various purposes, such as encapsulating flavors or improving food packaging.
Sodium carboxy methyl cellulose (E 466) is cost-effective and environmentally friendly because it is derived from renewable resources, such as wood pulp or cotton cellulose.
Sodium carboxy methyl cellulose (E 466) is used as a highly effective additive to improve the product and processing properties in various fields of application - from foodstuffs, cosmetics and pharmaceuticals to products for the paper and textile industries.
Sodium carboxy methyl cellulose (E 466) is non-toxic and non-allergenic, which contributes to its widespread use in food and pharmaceutical products.
Sodium carboxy methyl cellulose (E 466) is highly hydrophilic, meaning it has a strong affinity for water.
Sodium carboxy methyl cellulose (E 466) also forms a complex with collagen and is capable of precipitating certain positively charged proteins.
Sodium carboxy methyl cellulose (E 466) is available as a white to almost white, odourless, tasteless, granular powder.
Sodium carboxy methyl cellulose (E 466) is an anionic polymer with a clarified solution dissolved in cold or hot water.
Sodium carboxy methyl cellulose (E 466) functions as a thickening rheology modifier, moisture retention agent, texture/body building agent, suspension agent, and binding agent in personal products and toothpaste.
Food and pharmaceutical grade Carboxymethylcellulose is required by law to contain not less than 99.5% pure Sodium carboxy methyl cellulose (E 466) and a maximum of 0.5% of residual salts (sodium chloride and sodium glycolate).
The degree of substitution (DS) can vary between 0.2-1.5, although it is generally in the range of 0.6-0.95.
The DS determines the behaviour of Sodium carboxy methyl cellulose (E 466) in water: Grades with DS >0.6 form colloidal solutions in water that are transparent and clear, i.e the higher the content of carboxymethyl groups, the higher the solubility and smoother the solutions obtained.
Sodium carboxy methyl cellulose (E 466) was first obtained in 1918 by the German and is granted a patent in 1921.
Sodium carboxy methyl cellulose (E 466) to achieve commercial production since 1921 in Europe.
But Sodium carboxy methyl cellulose (E 466) was only for the crude product which was used as colloid and binder.
From 1936 to 1941, the industrial applied research of Sodium carboxy methyl cellulose (E 466) is very active, people invented several enlightening patents.
German use Sodium carboxy methyl cellulose (E 466) for synthetic detergent during World War II.
In 1943, Sodium carboxy methyl cellulose (E 466) was first made by Hercules Company in the United States and produced the refined product’s sodium in 1946 which are recognized as safe food ingredients.
Sodium carboxy methyl cellulose (E 466) is the most widely used and the largest amount of fiber in the worlds.
Uses:
Sodium carboxy methyl cellulose (E 466) is used as viscosity modifiers to stabilize the emulsions.
Sodium carboxy methyl cellulose (E 466) is used as a lubricant in artificial tears and it is used to characterize enzyme activity from endoglucanases.
Sodium carboxy methyl cellulose (E 466) is used in a variety of applications ranging from food production to medical treatments.
Sodium carboxy methyl cellulose (E 466) is commonly used as a viscosity modifier or thickener, and to stabilize emulsions in various products, both food and non-food.
Sodium carboxy methyl cellulose (E 466) is used primarily because it has high viscosity, is nontoxic, and is generally considered to be hypoallergenic, as the major source fiber is either softwood pulp or cotton linter.
Sodium carboxy methyl cellulose (E 466) used as sizing agent and printing paste in printing and dyeing industry.
Sodium carboxy methyl cellulose (E 466) can be used as a component of oil recovery fracturing fluid in the petrochemical industry.
Sodium carboxy methyl cellulose (E 466) is a widely used ionic cellulose ether, widely used in petroleum, food, medicine, construction and ceramics industries, so it is also known as "industrial monosodium glutamate".
Sodium carboxy methyl cellulose (E 466) is frequently used as a thickening agent in a wide range of food products, such as salad dressings, sauces, and ice cream.
Sodium carboxy methyl cellulose (E 466) imparts viscosity and helps to stabilize these products.
Sodium carboxy methyl cellulose (E 466) molecules, negatively charged at wine pH, interact with the electropositive surface of the crystals, where potassium ions are accumulated.
The slower growth of the crystals and the modification of their shape are caused by the competition between Sodium carboxy methyl cellulose (E 466) molecules and bitartrate ions for binding to the KHT crystals.
Sodium carboxy methyl cellulose (E 466) powder is widely used in the ice cream industry, to make ice creams without churning or extremely low temperatures, thereby eliminating the need for conventional churners or salt ice mixes.
Sodium carboxy methyl cellulose (E 466) is used in baking breads and cakes.
The use of Sodium carboxy methyl cellulose (E 466) gives the loaf an improved quality at a reduced cost, by reducing the need of fat.
Sodium carboxy methyl cellulose (E 466) is also used as an emulsifier in biscuits.
Non-food products include products such as toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, reusable heat packs, various paper products, filtration materials, synthetic membranes, wound healing applications, and also in leather crafting to help burnish edges.
Sodium carboxy methyl cellulose (E 466) is used in food under the E number E466 or E469 (when it is enzymatically hydrolyzed), as a viscosity modifier or thickener, and to stabilize emulsions in various products, including ice cream.
Sodium carboxy methyl cellulose (E 466) is also used extensively in gluten-free and reduced-fat food products.
Sodium carboxy methyl cellulose (E 466) is used to achieve tartrate or cold stability in wine, an innovation that may save megawatts of electricity used to chill wine in warm climates.
Sodium carboxy methyl cellulose (E 466) is more stable than metatartaric acid and is very effective in inhibiting tartrate precipitation.
Sodium carboxy methyl cellulose (E 466) is reported that KHT crystals, in presence of CMC, grow slower and change their morphology.
Their shape becomes flatter because they lose 2 of the 7 faces, changing their dimensions.
Constituents are any of several fibrous substances consisting of the chief part of a plant’s cell walls (often extracted from wood pulp or cotton).
Sodium carboxy methyl cellulose (E 466) salt is used in drilling muds, in detergents as a soil-suspending agent, in resin emulsion paints, adhesives, printing inks, textile sizes and protective colloid.
Sodium carboxy methyl cellulose (E 466) acts as a stabilizer in foods.
Sodium carboxy methyl cellulose (E 466) is also employed in pharmaceuticals as a suspending agent and excipients for tablets.
Sodium carboxy methyl cellulose (E 466) can be used as soap and washing powder detergent active additives, as well as other industrial production on the dispersion, emulsification, stability, suspension, film, paper, polishing and the like.
Quality product can be used for toothpaste, medicine, food and other industrial sectors.
Sodium carboxy methyl cellulose (E 466) is frequently called simply carboxymethyl cellulose and also known as cellulose gum.
Sodium carboxy methyl cellulose (E 466) is derived from purified cellulose from cotton and wood pulp.
Sodium carboxy methyl cellulose (E 466) is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.
Sodium carboxy methyl cellulose (E 466) is a hygroscopic material that has the ability to absorb more than 50% of water at high humidity.
Sodium carboxy methyl cellulose (E 466) can also help to reduce the amount of egg yolk or fat used in making the biscuits.
Use of Sodium carboxy methyl cellulose (E 466) in candy preparation ensures smooth dispersion in flavor oils, and improves texture and quality.
Sodium carboxy methyl cellulose (E 466) is used in chewing gums, margarines and peanut butter as an emulsifier.
Sodium carboxy methyl cellulose (E 466) has been used extensively to characterize enzyme activity from endoglucanases (part of the cellulase complex); it is a highly specific substrate for endo-acting cellulases, as its structure has been engineered to decrystallize cellulose and create amorphous sites that are ideal for endoglucanase action.
Sodium carboxy methyl cellulose (E 466) is used as a soil suspension polymer designed to deposit onto cotton and other cellulosic fabrics, creating a negatively charged barrier to soils in the wash solution.
Sodium carboxy methyl cellulose (E 466) is also used as a thickening agent, for example, in the oil-drilling industry as an ingredient of drilling mud, where it acts as a viscosity modifier and water retention agent.
Sodium carboxy methyl cellulose (E 466) is also a natural polymeric derivative that can be used in detergents, food and textile industries.
Sodium carboxy methyl cellulose (E 466) can be used as a binder in the preparation of graphene nano-platelet based inks for the fabrication of dye sensitized solar cells (DSSCs).
Sodium carboxy methyl cellulose (E 466) can also be used as a viscosity enhancer in the development of tyrosinase based inks for the formation of electrodes for biosensor applications.
Sodium carboxy methyl cellulose (E 466) is sometimes used as an electrode binder in advanced battery applications (i.e. lithium ion batteries), especially with graphite anodes.
Sodium carboxy methyl cellulose (E 466)'s water solubility allows for less toxic and costly processing than with non-water-soluble binders, like the traditional polyvinylidene fluoride (PVDF), which requires toxic n-methylpyrrolidone (NMP) for processing.
Sodium carboxy methyl cellulose (E 466) is often used in conjunction with styrene-butadiene rubber (SBR) for electrodes requiring extra flexibility, e.g. for use with silicon-containing anodes.
Sodium carboxy methyl cellulose (E 466) is also used in ice packs to form a eutectic mixture resulting in a lower freezing point, and therefore more cooling capacity than ice.
Aqueous solutions of Sodium carboxy methyl cellulose (E 466) have also been used to disperse carbon nanotubes, where the long Sodium carboxy methyl cellulose (E 466) molecules are thought to wrap around the nanotubes, allowing them to be dispersed in water.
a-CMC (Sodium carboxy methyl cellulose (E 466)) acts as a stabilizer and prevents ingredients from separating in products like beverages, including soft drinks and fruit juices.
In salad dressings, Sodium carboxy methyl cellulose (E 466) helps create stable emulsions of oil and water, preventing them from separating.
In the pharmaceutical industry, Sodium carboxy methyl cellulose (E 466) can be used as a binder in tablet formulations to hold the ingredients together.
In oral suspensions and liquid medications, Sodium carboxy methyl cellulose (E 466) helps to suspend solid particles uniformly in the liquid, ensuring consistent dosing.
In cosmetics and personal care products, Sodium carboxy methyl cellulose (E 466) can be used to improve the moisture retention properties of creams and lotions.
Sodium carboxy methyl cellulose (E 466) is used in paper manufacturing to coat the surface of paper, improving its printability and smoothness.
Sodium carboxy methyl cellulose (E 466) is sometimes used in the textile industry as a sizing agent to improve the weaving process.
For its thickening and swelling properties, Sodium carboxy methyl cellulose (E 466) is used in a variety of intricately formulated products for the pharmaceutical, food, home, and personal care industries as well as the paper, water treatment, and mineral processing industries.
Thorough knowledge of the concentration-dependent rheology and relaxation response is required to design Sodium carboxy methyl cellulose (E 466) solutions for applications.
Alkali cellulose and sodium chloroacetate react to form a gummy substance that is either soluble in water or swells in water.
Sodium carboxy methyl cellulose (E 466) is primarily used as a thickening, emulsifying, and stabilizing agent (as in sizes for textiles and paper and pharmaceutical ointments) as well as a bulk laxative and antacid in medicine.
In conservation-restoration, Sodium carboxy methyl cellulose (E 466) is used as an adhesive or fixative (commercial name Walocel, Klucel).
Sodium carboxy methyl cellulose (E 466) is used as a support material for a variety of cathodes and anodes for microbial fuel cells.
Sodium carboxy methyl cellulose (E 466) is used in refractory fiber, ceramic production molding bond.
Sodium carboxy methyl cellulose (E 466) can be used as a flocculant, chelator, emulsifier, thickener, water-retentive, sizing, and film-forming substance, among other things.
Electronics, pesticides, leather, plastics, printing, ceramics, and the daily-use chemical industry are just a few of the industries that heavily utilize Sodium carboxy methyl cellulose (E 466).
Additionally, Sodium carboxy methyl cellulose (E 466) has a wide range of applications due to its excellent properties, widespread use, and emerging potential fields.
Sodium carboxy methyl cellulose (E 466) is used in oil drilling, exploration address slurry thickening, reducing water loss, quality paper surface sizing.
Sodium carboxy methyl cellulose (E 466) is resistant to bacterial decomposition and provides a product with uniform viscosity.
Sodium carboxy methyl cellulose (E 466) can prevent skin moisture loss by forming a film on the skin’s surface, and also help mask odor in a cosmetic product.
Storage:
In tablets, this has been associated with a decrease in tablet hardness and an increase in disintegration time.
However, this process results in a significant decrease in viscosity and some deterioration in the properties of solutions prepared from the sterilized material.
Aqueous solutions are stable at pH 2–10; precipitation can occur below pH 2, and solution viscosity decreases rapidly above pH 10.
Generally, solutions exhibit maximum viscosity and stability at pH 7–9.
Sodium carboxy methyl cellulose (E 466) may be sterilized in the dry state by maintaining it at a temperature of 1608℃ for 1 hour.
Sodium carboxy methyl cellulose (E 466) is a stable, though hygroscopic material. Under high-humidity conditions, carboxymethylcellulose sodium can absorb a large quantity (>50%) of water.
Safety Profile:
Sodium carboxy methyl cellulose (E 466) is also widely used in cosmetics, toiletries, and food products, and is generally regarded as a nontoxic and nonirritant material.
Hypersensitivity and anaphylactic reactions have occurred in cattle and horses, which have been attributed to Sodium carboxy methyl cellulose (E 466)m in parenteral formulations such as vaccines and penicillins.
Sodium carboxy methyl cellulose (E 466) is used in oral, topical, and some parenteral formulations.
The WHO has not specified an acceptable daily intake for Sodium carboxy methyl cellulose (E 466) as a food additive since the levels necessary to achieve a desired effect were not considered to be a hazard to health.
However, oral consumption of large amounts of Sodium carboxy methyl cellulose (E 466) can have a laxative effect; therapeutically, 4–10 g in daily divided doses of the medium- and high-viscosity grades of carboxymethylcellulose sodium have been used as bulk laxatives.
However, in animal studies, subcutaneous administration of Sodium carboxy methyl cellulose (E 466) has been found to cause inflammation, and in some cases of repeated injection fibrosarcomas have been found at the site of injection.
